Anorexia Nervosa

Man versus machine? Acquired long QT syndrome in a patient with anorexia nervosa

Annals of Noninvasive Electrocardiology
By Philip S. Mehler, MD, FACP, FAED, CEDS

Abstract

Computer‐generated Bazett‐corrected QT (QTcB) algorithms are common in clinical practice and can rapidly identify repolarization abnormalities, but accuracy is variable. This report highlights marked rate‐corrected QT (QTc) interval prolongation not detected by the computer algorithm. A 26‐year‐old woman with anorexia nervosa was admitted with severe hypokalemia and ventricular ectopy. Computer‐generated QTcB was 485 ms, while manual adjudication yielded a QTcB of 657 ms and a Fridericia‐corrected QT (QTcF) interval of 626 ms using digital calipers. Computer‐generated QTc intervals may aid in clinical decision‐making. However, accuracy is variable, particularly in the setting of ectopy, and requires manual verification.

DOI:
https://doi.org/10.1111%2Fanec.12704
Written by
Philip S. Mehler, MD, FACP, FAED, CEDS

Philip S. Mehler, MD, FACP, FAED, CEDS

Dr. Philip Mehler, MD, FACP, FAED, CEDS founded the ACUTE Center for Eating Disorders and Severe Malnutrition in 2001 and serves as its Executive Medical Director. He began his career at Denver Health…

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